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The U‑2D™ system is a glass‑insert management solution for autosampler vial users that applies the convenience of a 96‑position format without replacing traditional plates or autosampler workflows. It is designed for laboratories that rely on glass inserts for chromatography, while needing a more efficient way to fill, inspect, manage, and transfer micro‑volume samples.

U‑2D™ is not intended to replace traditional 96‑well plates. Instead, it provides a structured format for handling individual glass autosampler‑grade inserts using familiar plate‑style tools and processes. Each position in the U‑2D™ rack holds a precision glass insert, allowing samples to be prepared, visually inspected, and managed in parallel—then transferred directly into standard autosampler vials when needed.


How the U‑2D™ System Works

The U‑2D™ system uses a removable rack of 96 glass inserts seated in a reusable base. Inserts may be handled as a group or individually, depending on the workflow.

Each insert:

  • Is autosampler‑grade glass, not plastic

  • Can be filled, inspected, and staged while still in the rack

  • Can be removed individually and placed into compatible 9 mm screw‑top autosampler vials for injection, storage, or transport

This approach preserves existing autosampler vial workflows while significantly improving micro‑sample handling efficiency.


Designed for Autosampler Insert Workflows

U‑2D™ supports the same workflows laboratories already use—but with improved control:

  • Glass‑first sampling – Maintains the chemical resistance, cleanliness, and visibility of glass inserts

  • Parallel handling – Process multiple samples simultaneously without switching to plastic plates

  • Direct vial transfer – Inserts move directly into autosampler vials with no repackaging

  • Visual inspection – Clear glass allows inspection of sample bottoms, particulates, or anomalies before injection


Functional Advantages

  • Same autosampler workflow, higher throughput

  • Reduced solvent usage and waste through precise micro‑volume handling

  • Improved thermal uniformity compared to traditional vial‑by‑vial handling

  • Ultra‑compact footprint relative to conventional insert storage systems


Smart, Modular Design

  • Removable insert rack allows full visual inspection or group transfer

  • Individual insert access — inserts can be pushed out from below without tools

  • Secure vial compatibility — each insert fits precisely into compatible AQ™ or RSA™ 9 mm screw‑top autosampler vials


Where U‑2D™ Excels

U‑2D™ is commonly used in:

  • LC‑MS and trace analysis

  • Bioanalytical and pharmaceutical workflows

  • Standards preparation and QC

  • Stability and dissolution studies

  • Any workflow relying on small volumes in glass inserts

It combines insert‑level precision with plate‑style efficiency, without changing how samples ultimately enter the autosampler.


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