The U‑2D™ system is a glass‑insert management solution for autosampler vial users that applies the convenience of a 96‑position format without replacing traditional plates or autosampler workflows. It is designed for laboratories that rely on glass inserts for chromatography, while needing a more efficient way to fill, inspect, manage, and transfer micro‑volume samples.
U‑2D™ is not intended to replace traditional 96‑well plates. Instead, it provides a structured format for handling individual glass autosampler‑grade inserts using familiar plate‑style tools and processes. Each position in the U‑2D™ rack holds a precision glass insert, allowing samples to be prepared, visually inspected, and managed in parallel—then transferred directly into standard autosampler vials when needed.
How the U‑2D™ System Works
The U‑2D™ system uses a removable rack of 96 glass inserts seated in a reusable base. Inserts may be handled as a group or individually, depending on the workflow.
Each insert:
Is autosampler‑grade glass, not plastic
Can be filled, inspected, and staged while still in the rack
Can be removed individually and placed into compatible 9 mm screw‑top autosampler vials for injection, storage, or transport
This approach preserves existing autosampler vial workflows while significantly improving micro‑sample handling efficiency.
Designed for Autosampler Insert Workflows
U‑2D™ supports the same workflows laboratories already use—but with improved control:
Glass‑first sampling – Maintains the chemical resistance, cleanliness, and visibility of glass inserts
Parallel handling – Process multiple samples simultaneously without switching to plastic plates
Direct vial transfer – Inserts move directly into autosampler vials with no repackaging
Visual inspection – Clear glass allows inspection of sample bottoms, particulates, or anomalies before injection
Functional Advantages
Same autosampler workflow, higher throughput
Reduced solvent usage and waste through precise micro‑volume handling
Improved thermal uniformity compared to traditional vial‑by‑vial handling
Ultra‑compact footprint relative to conventional insert storage systems
Smart, Modular Design
Removable insert rack allows full visual inspection or group transfer
Individual insert access — inserts can be pushed out from below without tools
Secure vial compatibility — each insert fits precisely into compatible AQ™ or RSA™ 9 mm screw‑top autosampler vials
Where U‑2D™ Excels
U‑2D™ is commonly used in:
LC‑MS and trace analysis
Bioanalytical and pharmaceutical workflows
Standards preparation and QC
Stability and dissolution studies
Any workflow relying on small volumes in glass inserts
It combines insert‑level precision with plate‑style efficiency, without changing how samples ultimately enter the autosampler.
Additional Resources
Explore traditional 96‑well plates and sealing mats for chromatography
View U‑2D™ RSA‑Pro X™ surface‑treated inserts and racks for glass‑sensitive analytes